RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
CASC2
RNA ID
ENSG00000177640
RNA Type
lncrna
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
qPCR; dual-luciferase reporter assay
Target
SOCS2
Pathway
JAK-STAT SIGNALING PATHWAY
PubMed ID
33227790
Title
LncRNA CASC2 Alleviates the Progression of Diabetic Nephropathy by Regulating the miR-144/SOCS2 Signalling Axis
Year
2020
Function
"Casc2 could alleviate the degree and process of apoptosis, inflammation, and fibrosis in diabetic nephropathic models by regulating the miR-144/socs2 axis."